Interleukin-28B (also named interferon-lambda 3, IFN-lambda 3), IL-28A (IFN-lambda 2) and IL-29 (IFN-lambda 1) are type III interferons that are class II cytokine receptor ligands. Product Properties Synonyms interleukin-28B; IFN-lambda 3; IL28B; IL-28B; IL28C; interferon, lambda 3 Uniprot No. AAN28264 Source Human IL-28B Protein is expressed from HEK293 without tag. It contains Arg30-Val200. Molecular Weight The protein has a predicted 19.6 kDa Purity > 95% as determined by SDS-PAGE. Biological Activity Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.1-0.5 ng/mL. Endotoxin < 0.01 EU per 1 μg of the protein by the LAL method. Formulation Dissolved in sterile PBS buffer. This solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening. Shipping and Storage The product should be stored at -85~-65℃ for 1 year from date of receipt. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles. Figure Figure 1.Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus.The EC50 for this effect is 0.1-0.5 ng/mL. Figure 2.4 ug/lane protein was resolved with SDS-PAGE under non-reducing (NR) and reducing (R) conditions and visualized by Coomassie Blue staining. Cautions 1. Please operate with lab coats and disposable gloves,for your safety. 2. This product is for research use only.
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