The interleukin (IL)-1 cytokine family currently consists of 11 members with pleiotropic functions in inflammation and cancer.IL-1α and IL-1β were the first members of the IL-1 family to be described, and they both signal through the same receptor, IL-1R. Product Properties Synonyms Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; IL-1 ALPHA; IL1; IL-1A; IL1 Species Mouse Source HEK293 Sequence Ser115-Ser270 Accession P01582 Tag C-His Molecular Weight The protein has a predicted MW of 19.08 kDa. Due to glycosylation, the protein migrates to 24-30 kDa based on Bis-Tris PAGE result. Endotoxin < 1 EU/μg by the LAL method. Purity > 95% as determined by Bis-Tris PAGE and HPLC Activity SPR Data: Mouse IL-1R1, His Tag immobilized on CM5 Chip can bind Mouse IL-1 alpha, His Tag with an affinity constant of 51.22 nM as determined in SPR assay. Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. Appearance Lyophilized powder Shipping and Storage -25 ~ -15 ° C storage, 1 year expiration date after receipt. After re-solution, store at 2 ~8 °C, 7 days expiration date. After re-dissolution, store at -85~-65°C, 3 months expiration date. Compounding method Centrifuge before opening the lid. Use distilled water to reconstitute lyophilized proteins at reconstitution concentrations greater than 100 μg/mL. it is recommended that proteins be portioned out for each experimental dosage upon first use to avoid repeated freeze-thawing. Cautions 1. For your safety and health, please wear lab coat and disposable gloves. 2. This product is for scientific research purposes only.
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