Recombinant Mouse TNFa Protein(HEK293) _ 90257ES

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Tumor necrosis factor alpha (TNF-α ), also known as malathin and TNFSF2, is the prototypical ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role i n inflammation, immune system development, apoptosis and lipid metabolism. In ECD, mouse TNF-α shares 94% amino acid sequence identity with rat, and 70%-77% amino acid sequence identity with bovine, canine, cotton rat, equine, feline, human, porcine, rat, and rhesus monkey TNF-α is produced by a wide variety of immune cells, epithelial, endothelial, and tumor cells. This product is supplied as Liquid, high activity, high purity, low endotoxin, No labeling. Product Properties Synonyms TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNFATNF; TNFG1F; TNFSF1A; TNFSF2; tumor necrosis factor alpha; Species Mouse Source HEK293 Ceslls Sequence Leu80-Leu235 Accession P06804 Tag No Predicted molecularmass 17.3 KDa Endotoxin 95%, determined by SDS-PAGE Activity Measured in a cytotoxicity assay using L929 mouse fibroblast cells .The ED50 for this effect is 8-50 pg/mL. Formulation Dissolved in sterile PBS buffer. Appearance Liquid Shipping and Storage -85~-65℃ storage, valid for 1 year after receipt. Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃. Cautions 1. For your safety and health, please wear lab coat and disposable gloves. 2. This product is for scientific research purposes only. Show more