Interleukin 2 (IL-2) is a potent immunomodulatory lymphokine produced by T cells in response to antigenic or mitogenic stimuli.IL-2/IL-2R signaling is required for T cell proliferation and other essential functions necessary for immune response.IL-2 stimulates B cell, NK cell, lymphokine-activated killer cell, monocyte, macrophage and oligodendrocyte growth and differentiation.IL-2 is used in the field of cell and gene therapy to promote the proliferation and differentiation of CAR-T cells, TCR-T cells, regulatory T cells, TIL cells, NK cells and CIK cells. This recombinant human IL-2, supplied as Lyophilized powder, is highly active, highly pure, low endotoxin, and NO labeled. Product Properties Synonyms IL2, T-cell Growth Factor, TCGF, Aldesleukin Species Human Source CHO Cells Sequence Ala21-Thr153 Accession P60568-1 Tag NO Molecular Weight Predicted molecular mass：15.4 kDa Endotoxin ≤10 EU/mg by the LAL method Purity ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining) Activity ≥1 x 107IU/mg. Measured in a cell proliferation assay using CTLL-2 mousecytotoxic T cells Formulation Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% mannitoland 0.01% Tween 80, pH 7.4 Appearance Lyophilized powder Shipping and Storage -25 ~ -15 ° C storage, from the date of receipt of goods, the expiration date of 1 year. After re-solution, store at 2 ~8 °C, 7-10 days expiration date. After re-dissolution, -85 ~ -65 ° C storage, 6 months expiration date. Figure Figure 1.Recombinant Human IL-2 stimulates proliferation of CTLL-2 cells. The specific activity is ≥1 x 10^7 IU/mg. Figure 2.Highly consistent bioactivity between different production batches of Recombinant Human IL-2 . Figure 3.Human IL-2 on SDS-PAGE under reduced(R) & Non-reducing(NR) condition. The purity is greater than 95%. Compounding method Use NO bacterial deionized water to reconstitute lyophilized proteins. It is recommended that proteins be divided for first use to avoid repeated freeze-thawing. Cautions 1. For your safety and health, please wear lab coat and disposable gloves. 2. This product is for scientific research purposes only.
