CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152 (Cluster of Differentiation 152 is), a protein receptor that downregulates immune responses. As a member of the immunoglobulin superfamily, CTLA-4 is expressed on the surface of helper T cells and delivers an inhibitory signal to regulate T cell activity . Structurally, the protein comprises an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Specifications Cat.No. 96526ES25 / 96526ES60 / 96526ES76 Size 25 μg / 100 μg / 500 μg Components Name 96526ES25 96526ES60 96526ES76 Recombinant Human BDCA2/DLEC4C Protein,hFc Tag 25 μg 100 μg 500 μg Performance parameters Synonyms Celiac Disease 3,CD152,CTLA4,CTLA-4 Species Mouse Expression Sequence: Glu36-Asp161 with His & Avi Tag at C-Terminus Accession P09793 Tag C-His-Avi Tag Expression System HEK293 Molecular Weight 25-30 kDa (Reducing) Purity > 95% as determined by SDS-PAGE. Endotoxin < 1.0 EU per μg by the LAL method. Formulation PBS, PH7.4, 5% trehalose Appearance Lyophilized Powder Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. Storage Store at -25°C to -15°C for 1 year upon receipt; after reconstitution under aseptic conditions, the product is stable for 7 days at 2°C to 8°C or for 3 months at -85°C to -65°C. Product Features High Activity & Purity, Low Endotoxin, High Lot-to-Lot Consistency. Application Example ELISA Data: Immobilized B7-1/CD80 Fc Chimera Protein,Mouse at 5.0 μg/mL (100 μL/well) can bind Biotinylated CTLA-4/CD152 His&Avi Tag Protein,Mouse with EC50 of 6.38-9.26 ng/mL. Notes 1. This product is for research use only. 2. Please operate with lab coats and disposable gloves, for your safety. Documents: Manual 96526_Manual_HB20260407