Protein A/G MagBeads use "nano-surface biotechnology" (S-TEC) to target Protein A/G onto the surface of superparamagnetic polymer microspheres with high density. It has higher antibody binding ability and very low non-specific adsorption rate of protein. One-step purification can isolate the antibody with purity >90% from the serum sample, which is simple and effective to use. Natural Protein A is a cell wall surface protein found in Staphylococcus aureus. Natural Protein G is a cell surface protein isolated from the genus G or C Streptococcus. Both have similar functions and bind most mammalian IgG by interacting primarily with the Fc region of immunoglobulin (Ig), but differ in their binding specificity. Protein A/G MagBeads covalently conjugate both protein A and protein G, providing A wider binding range and higher utility than either protein A or protein G alone. At the same time, this product uses genetically modified proteins A and G, which not only maintain their Ig affinity properties, but also remove the non-major binding domain of the natural protein itself to reduce non-specific binding. This product has a wide range of application, can be used in cell lysis fluid, cell secretory fluid supernatant, serum, animal ascites and other immune antigen samples. Yeasen offers comprehensive solutions for protein purification experiments. Explore our related products: Antibody Capture Tool: Easily Handle IP and Co-IP with Protein A/G Agarose and Magnetic Beads Features Low background—little to no nonspecific binding, and no preclearing Highly reproducible—uniform beads ensure the most consistent results Highly sensitive—Magbeads technology is the most cited method for sensitive applications, such as ChIP and IP, of low abundance proteins Fast and easy— no centrifugation or preclearing steps Versatile—products for IP, Co-IP, pull-down, and ChIP assays. Applications Immunoprecipitation (IP) Purification of antibody Specifications Ligand Protein A/G Binding Capacity ≥50 μg hIgG /mg Particle size 1 μm Concentration 10 mg/mL Storage Buffer PBS, 0.01% Tween-20, 0.02% NaN3 Smaller beads, Higher capacity Supplier T* Protein G/Protein A Yeasen Protein A/G MagBeads, 36417ES Diameter 2.8 μm 1 μm Concentration 30 mg/mL 10 mg/mL Capacity About 8 µg human IgG/mg beads About 50µg human IgG /mg beads Components Components No. Name 36417ES03 36417ES08 36417 Protein A/G MagBeads (IP Grade) 1 mL 5 mL Figures Cited from: Thoracic cancer 11, 1848-1860, 2020 Cited from: Mol Biotechnol 65, 1296–1305 (2023) Cited from: The Plant Cell, 2025, 37 Cited from: Molecular Therapy, 30, 448 - 467 Cited from: Oncogene. 2022;41(10):1482-91 The SDS-PAGE gel electrophoresis results of Rabbit serum purification by Protein A/G MagBeads (IP Grade).L: sample, L: eluate.
