Human FGFR4 Protein, His tag

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Fibroblast growth factor receptor 4 (FGFR4) is also known as CD334. A member of the fibroblast growth factor receptor family, its amino acid sequence is highly conserved among memb ers and throughout evolution. These receptor proteins play a role in important processes such as cell division, regulation of cell growth and maturation, blood vessel formation, wound healing, and embryonic development. The exact function of FGFR4 remains unclear, but studies have shown that the gene is involved in muscle development and maturation of calvarial osteocytes, and the protein is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. Specifications Synonyms CD334;FGFR4,CD334,JTK2,MGC20292,TKF Uniprot No. P22455-1 Source Recombinant Human FGFR4 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Leu 22 - Asp 369 Molecular Weight The protein has a predicted MW of 39.3 kDa. And it migrates as 50-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity > 95% as determined by SDS-PAGE. Endotoxin Show more